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Aziz Denian, M.D.

Denian during his fellowship training with Professor Brandstater at the Stroke Management Unit, Loma Linda University Hospital, California, in 2003.

Aziz Denian, M.D., currently runs the Denian Clinic, a private practice for neurorehabilitation, pain management and mesotheraphy services in Amman,
Jordan. The neurorehabilitation program is a combination of neurological and behavioral assessment, followed by treatment with a medicinal and/or
brain stimulation series designed to alleviate the effects of pain or memory loss. The clinic's mesotherapy program provides therapies to improve skin
abnormalities and imperfections due to aging and/or disease. Currently, Denian is investigating methods to stimulate brain regeneration, particularly in
Alzheimer's and post-traumatic brain injuries.

Denian received his M.D. from Yerevan Medical School, Armenia, in 1985. From 1985-2007, Denian worked for the Royal Medical Services of  Jordan
as a Consultant in Neurorehabilitiation, Pain and Antiaging Medicine. He received the Clinical and Research Fellowship in General & Neurological
Rehabilitation Medicine from Loma Linda University Medical School in 2003-2004, and presented his work in the 2003 annual meeting of the
Association of Academic Psychiatrists. Denian began training courses in mesotheraphy at Bordeaux II University, France in 2004, and he resigned from
his position at Royal Medical Services to open the Denian Clinic in 2007.

Denian receives his Mesotherapy Certificate with Professor Petit (France) and Professor Silva (Argentina) from Bordeaux II University, France, 2004.

Occupation and research interests

Currently, I am successfully practicing aesthetic mesotherapy to treat wrinkles, lines, stretch marks and cellulite. Additionally, I am practicing therapeutic
mesotherapy for neuro-musculoskeletal regenerative conditions and pain management.
At the same time I am reestablishing my scientific investigations by self-proposed methods to stimulate brain regeneration in cases of Alzheimer's and
post-traumatic brain injuries, with preliminary but promising results. Also, I am investigating the improvement of injection methods in blocking headaches
by peri-scalp and peripheral feedback subcutaneous injections (mixtures consisting of FDA approved medications). I am planning to re-introduce low
frequency electromagnetic fields to my practice in parallel.  
My research involves pathologies related to amnesia, dementia and other cognitive acquired defects. Current brain stimulation and renormalization with
the available knowledge remains generalized with the neural and vascular components within the brain.

What were your motivations in pursuing the clinical side of neuroregenerative therapies?

While being at Loma Linda University, California, for my fellowship training, I participated in the academic and research activities with Professor Murray
Brandstater and colleagues. I worked at the adult and child spasticity clinics and pain management clinics with surgical pain management invasive
injections, neuro-blocking procedures, pain-spasticity implanted electronic pumps, Botox and other blockers. I was trained on the management of
stroke and traumatic brain injuries, therapies for cerebral palsy patients, and on using the medications within these fields. I participated at the
electrophysiological clinics where I enrolled in the preparation of two clinical studies on spasticity and coagulation in stroke, and was actively involved in
a spasticity study on TBI. During this time I realized my capabilities in the medical sciences and I realized the possibilities of achieving a breakthrough in
medical science.
Professor Murray Brandstater's approach for his patients and his dedication for his work and science influenced me in my practice, and influenced me
to utilize my scientific potential.

What are a few short term goals in your clinical practice?

I have practiced medicine since 1985. My current work at my private clinic does not limit my potential; it gives me more time for thinking, studying and to
work on becoming more creative. The methods I am using consist of minimally invasive medication mixtures injected subcutaneously and intradermaly
in specific distributions. I am planning to arrange for other medical technologies in parallel to my injection methods and smart medications for the
stimulation and normalization of the diseased brain, as well as for the treatment of multiple types of headaches.

I will be designing a lab budget to study the outcome of my clinical management at the cellular, chemical and pharmacological levels, in the near future.
This is essential so as to understand and explain my current and upcoming progress in the clinical improvement of my CNS and PNS diseased patients.

In regards to future developments, what type of neuroregenerative breakthroughs do you predict?

Brain regeneration studies are still in the headlines. Almost all the available antagonists, blockers, stimulators and suppressors are being studied; in
memory, complex gate coordination and control, muscle tone, behaviors, etc. I don’t think that a specific treatment would solve a single or a couple of
the brain defective functions, at least in the near future.

I can predict in what I believe, and what I predict is what we could do right now, until the opportunities for specific treatments become
more likely. Currently, I predict that brain stimulation by external factors such as renormalization, plus stimulating the auto-regenerative and metabolic
mechanisms such as with the targeted surface injections, and using the smart group medications, to smoothly stimulate the brain circulation and
enhancement of the neural cell metabolism, is so far the most comprehensive combination available.

Currently, I have preliminary but promising clinical results. I have some achievements in accelerating the healing of locked-in patients, and
accelerating some localized (isolated) motor improvements in TBI and stroke. For headaches, I am achieving tremendous results in the treatment of my
patients, both with migraines and cluster and tension headaches. I have many patients with prolonged remissions as long as six months and with very
mild relapses thereafter.

Finally, the question that I am frequently asking myself is this: “I am able with my injections to interfere and alleviate a migraine for a few months, which
is a vascular and chemically mediated pathological condition. Therefore, I should be able with the same technique, in use with other technologies, to
interfere and correct more specific vascular and metabolic dysfunctions of the brain. Could I interfere with the degenerative process? At this point, I
think that a multidisciplinary research team, surrounded with the best available technology, is mandatory for further achievements.           
To discuss clinical neurology and other topics with fellow Science Advisory Board members, please visit our community forum.

Dr. Denian's Clinic
This is a website for Denian's patients to gather more information on services offered and Denian's professional experience and publications.

Mesotherapy Center
This website is a work in progress, and will feature the details of an upcoming Mesotheraphy Center.

Dr Denian's Publications
Exploration Of “DenianTMD”. Previously unknown and unclassified type of Temporomandibular joint dysfunction TMD associated and predisposed by
the systemic hypermobility syndrome SHMS, Pan Arab Medical Journal, Vol 2. No 10. October-December 2007.

Civil War Amputees In Sierra Leone. A Prospective survey study on 145 survived amputee patients. Screening the levels, and predicting the demand
for proper re-evaluation, and Ortho- Neuro- Psychological comprehensive rehabilitation program. Pan Arab Medical Journal, Vol 2. No 8. Jan-March
2007, P57-63.

Local corticosteroid injections in the management of Pes-Anserine Bursitis, Prospective clinical study, Jordan Medical Journal, Vol 37. No 2. Nov 2003.

TMD due to muscle hyperlaxety. “Hypermobility syndrome” new case series recently presented during the Association Of Academic Physiatrists 2003
Annual Meeting/Fort Lauderdale, Florida, March 27-29, 2003. American Journal of Physical Medicine & Rehabilitation, Vol. 82. March 2003 # 3 p250.

Confirmation of the Median nerve entrapment at the carpal tunnel, Carpal tunnel syndrome "CTS", by the Nerve conduction study " NCS", Review of
144 patients. Journal Of The Royal Medical Services Dec-1999.
Aziz Denian, MD.
Science Advisory Bord Member Since 2002
With My Friend, Colleague And Mesotherapy
Teacher Professor Phillipe Petite From Bordeaux
University - France. During His Most Recent
Workshop In Amman About Facial Rejuvenation
Mesotherapy Injections Update & Facial Fillers
Sheraton Hotel - Amman Jordan - Nov 2010
Dr Denian's New Clinic June 2011  - Pls Click On Image 4 wide View
وقف المزيد من حب الشباب فورا و احتمال تحسن الندب
2011ايضا - انجازات رائعة   لعام      
Of Acne Scare Exists - New 2011
Plastic surgery on Estheticon.com
Updating July 2012 :- All Mesotherapy Line Medications Are New Formulas For Best Ever Meso Results Including Glutahtione, DAME, Na Pyruvate. All Most Recent Cellulite And
Fat Management Meso And Machines Are Updated Including The Cold LL Laser.
1sr March 2013: K-Laser USA Just Introduced Into Denian's Clinic Services (First Clinic In The Arab Countries)